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Hormone‐related events and periodontitis in women
Author(s) -
Romandini Mario,
Shin HyeSun,
Romandini Pierluigi,
Laforí Andreina,
Cordaro Massimo
Publication year - 2020
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13248
Subject(s) - medicine , periodontitis , menopause , breastfeeding , population , obstetrics , periodontium , dentistry , pediatrics , environmental health
Aim While the short‐term effects of hormonal events on gingival inflammation have been well described, long‐term effects on the periodontium have received less attention. The aim of this cross‐sectional population‐based study was to evaluate the association between hormone‐related events and periodontitis in a representative sample of the postmenopausal women of South Korea. Materials and Methods A total of 10,273 postmenopausal women representative of 6.1 million of Koreans were examined. Periodontitis and severe periodontitis were defined according to the Community Periodontal Index (CPI ≧ 3 and CPI = 4, respectively). Univariate and multivariate regression analyses using 3 different models were applied controlling for age, smoking, marital status, educational level, income, BMI, hypertension, stress and frequency of toothbrushing. Results Severe periodontitis was directly associated with a longer reproductive life ( p ‐trend = .027) and with a longer duration of breastfeeding (48–72 vs. 1–17 months: OR = 1.49; 95% CI: 1.01–2.21). Conversely, early menopausal age (<46 vs. 49–50 years: OR = 0.74; 95% CI: 0.56–0.97), history of artificial menopause (OR = 0.72; 95% CI: 0.53–0.97), having had more than 6 pregnancies (vs. 4: OR = 0.73; 95% CI: 0.55–0.97), having had more than three abortions (vs. 0: OR = 0.51; 95% CI: 0.28–0.93) and having had the first birth age >26 years (vs. <21 years: OR = 0.71; 95% CI: 0.52–0.97) were inversely associated with severe periodontitis. Conclusions In this large nationally representative population, severe periodontitis was related to menopausal age, reproductive life length, number of pregnancies/abortions, first birth age and breastfeeding duration, while it was not to oral contraceptive and hormone replacement therapy usages.