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Biological factors involved in alveolar bone regeneration
Author(s) -
Giannobile William V.,
Berglundh Tord,
AlNawas Bilal,
Araujo Mauricio,
Bartold P. Mark,
Bouchard Philippe,
Chapple Iain,
Gruber Reinhard,
Lundberg Pernilla,
Sculean Anton,
Lang Niklaus P.,
Lyngstadaas Petter,
Kebschull Moritz,
GalindoMoreno Pablo,
Schwartz Zvi,
Shapira Lior,
Stavropoulos Andreas,
Reseland Janne
Publication year - 2019
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13130
Subject(s) - osteoimmunology , dental alveolus , regeneration (biology) , dentistry , medicine , regenerative medicine , mesenchymal stem cell , pathology , stem cell , biology , microbiology and biotechnology , receptor , activator (genetics) , rankl
Background and Aims To describe the biology of alveolar bone regeneration. Material and Methods Four comprehensive reviews were performed on (a) mesenchymal cells and differentiation factors leading to bone formation; (b) the critical interplay between bone resorbing and formative cells; (c) the role of osteoimmunology in the formation and maintenance of alveolar bone; and (d) the self‐regenerative capacity following bone injury or tooth extraction were prepared prior to the workshop. Results and Conclusions This summary information adds to the fuller understanding of the alveolar bone regenerative response with implications to reconstructive procedures for patient oral rehabilitation. The group collectively formulated and addressed critical questions based on each of the reviews in this consensus report to advance the field. The report concludes with identified areas of future research.