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Predictors for tooth loss in periodontitis patients: Systematic review and meta‐analysis
Author(s) -
Helal Omar,
Göstemeyer Gerd,
Krois Joachim,
Fawzy El Sayed Karim,
Graetz Christian,
Schwendicke Falk
Publication year - 2019
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13118
Subject(s) - medicine , meta analysis , tooth loss , periodontitis , dentistry , clinical attachment loss , molar , oral health
Aim A range of predictors for tooth loss in periodontitis patients have been reported. We performed a systematic review and meta‐analysis to assess the consistency and magnitude of any association between a total of 12 predictors and tooth loss. Materials and Methods Medline/Embase/Central were searched for longitudinal studies investigating the association between predictors and tooth loss in periodontitis patients. Random‐effects meta‐analysis was performed, and study quality assessed. Results Twenty studies (15,422 patients, mean follow‐up: 12 years) were included. The mean annual tooth loss/patient was 0.12 (min./max: 0.01/0.36). Older patients ( n = 8 studies; OR : 1.05, 95% CI : 1.03–1.08/year), non‐compliant ones ( n = 11; 1.51, 1.06–2.16), diabetics ( n = 7; 1.80, 1.26–2.57), those with IL ‐1‐polymorphism ( n = 3; 1.80; 1.29–2.52) and smokers ( n = 15; 1.98, 1.58–2.48) had a significantly higher risk of tooth loss. Teeth with bone loss ( n = 3; 1.04, 1.03–1.05/%), high probing pocket depth ( n = 6; 3.19, 1.70–5.98), mobility ( n = 4; 3.71, 1.65–8.38) and molars ( n = 4; 4.22, 2.12–8.39), especially with furcation involvement ( n = 5; 2.68, 1.75–4.08) also showed higher risks. Gender ( n = 16; 0.95, 0.86–1.05) and endodontic affection ( n = 3; 3.62, 0.99–13.2) were not significantly associated with tooth loss. Conclusions Older, non‐compliant, smoking or diabetic patients, and teeth with bone loss, high probing pocket depth, mobility, or molars, especially with furcation involvement showed higher risks of tooth loss.