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Soft tissue substitutes to increase gingival thickness: Histologic and volumetric analyses in dogs
Author(s) -
Song Young Woo,
Kim Sungtae,
Waller Tobias,
Cha JaeKook,
Cho SungWon,
Jung UiWon,
Thoma Daniel S.
Publication year - 2019
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13034
Subject(s) - dentistry , histology , medicine , analysis of variance , soft tissue , incisor , molar , statistical analysis , hard tissue , orthodontics , pathology , mathematics , statistics
Objectives To evaluate the histologic and volumetric changes of gingival tissues following grafting with collagen‐based matrices at labial aspect of teeth in canines. Materials and Methods Gingival augmentation was performed in the mandibular incisor area using two types of xenogeneic cross‐linked collagen matrices ( CCM s), bovine CCM for BCCM group and porcine CCM for PCCM group, whereas the contralateral sides remained untreated (B‐control group and P‐control group). Descriptive histology, histometric and volumetric analyses were performed after 12 weeks. For statistical comparison between each test group and respective control group, paired t test was used for histometric analysis, and repeated‐measured analysis of variance was used for volumetric analysis ( p < 0.05). Results An increased number of rete pegs and an enhanced formation of new blood vessels were observed at both grafted sites compared to the corresponding control sites. There was statistically significant gain of horizontal thickness only in BCCM group (1.36 ± 0.27 mm vs. 1.26 ± 0.34 mm; p < 0.05) compared to the B‐control groups. Conclusion BCCM was effective for gingival augmentation in terms of horizontal thickness at the labial aspect of teeth at 12 weeks post‐surgery.