Premium
The effects of periodontal treatment on diabetic patients: The DIAPERIO randomized controlled trial
Author(s) -
Vergnes JeanNoel,
Canceill Thibault,
Vinel Alexia,
LaurencinDalicieux Sara,
MaupasSchwalm Françoise,
BlascoBaqué Vincent,
Hanaire Hélène,
Arrivé Elise,
Rigalleau Vincent,
Nabet Cathy,
Sixou Michel,
Gourdy Pierre,
Monsarrat Paul
Publication year - 2018
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.13003
Subject(s) - medicine , periodontitis , randomized controlled trial , confidence interval , quality of life (healthcare) , fructosamine , diabetes mellitus , dentistry , gingival and periodontal pocket , scaling and root planing , clinical trial , chronic periodontitis , insulin , endocrinology , nursing
Aim To assess whether periodontal treatment can lead to clinical, glycaemic control and quality of life improvements in metabolically unbalanced diabetic patients (type 1 or type 2) diagnosed with periodontitis. Methods In this open‐labelled randomized controlled trial, diabetic subjects ( n = 91) were given “immediate” or “delayed” periodontal treatment (full‐mouth non‐surgical scaling and root planing, systemic antibiotics, and oral health instructions). The main outcome was the effect on glycated haemoglobin (HbA 1C ) and fructosamine levels. The General Oral Health Assessment Index and the SF ‐36 index were used to assess quality of life (QoL). Results Periodontal health significantly improved after periodontal treatment ( p < 0.001). Periodontal treatment seemed to be safe but had no significant effects on glycaemic control based on HbA 1C (adjusted mean difference with a 95% confidence interval ( aMD ) of 0.04 [−0.16;0.24]) and fructosamine levels ( aMD 5.0 [−10.2;20.2]). There was no obvious evidence of improvement in general QoL after periodontal treatment. However, there was significant improvement in oral health‐related QoL ( aMD 7.0 [2.4;11.6], p = 0.003). Conclusion Although periodontal treatment showed no clinical effect on glycaemic control in this trial, important data were provided to support periodontal care among diabetic patients. Periodontal treatment is safe and improves oral health‐related QoL in patients living with diabetes. ISRCTN 15334496.