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The association between missing teeth and non‐alcoholic fatty liver disease in adults
Author(s) -
Qiao Feng,
Fu Kaiyu,
Zhang Qing,
Liu Li,
Meng Ge,
Wu Hongmei,
Xia Yang,
Bao Xue,
Gu Yeqing,
Shi Hongbin,
Sun Shaomei,
Wang Xing,
Zhou Ming,
Jia Qiyu,
Song Kun,
Niu Kaijun
Publication year - 2018
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12929
Subject(s) - medicine , odds ratio , fatty liver , confidence interval , tooth loss , logistic regression , gastroenterology , population , disease , dentistry , oral health , environmental health
Aims Long‐term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non‐alcoholic fatty liver disease ( NAFLD ). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD . This study evaluated the association between missing teeth and presence of NAFLD in a general population. Materials and Methods A cross‐sectional study of 24,470 adults was carried out from the Tianjin Chronic Low‐grade Systemic Inflammation and Health Cohort Study. The self‐reported number of missing teeth (excluding third molars) was recorded and classified into four categories: 0, 1–2, 3–5, and ≥6. The NAFLD was diagnosed by the liver ultrasonography. Associations were analysed by adjusted multivariable logistic regression. Results The multivariable‐adjusted odds ratios (95% confidence interval) of NAFLD across the categories of missing teeth were as follows: in males, 1.00 (reference), 1.04 (0.93–1.16), 1.06 (0.90–1.24), and 1.40 (1.09–1.81) ( p for trend = 0.04); in females, 1.00 (reference), 0.98 (0.83–1.15), 1.11 (0.90–1.37), and 1.07 (0.77–1.48) ( p for trend = 0.45). Conclusions The number of missing teeth was associated with a higher presence of NAFLD in males but not females.