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Chronic periodontitis is associated with erectile dysfunction. A case–control study in european population
Author(s) -
Martín Amada,
Bravo Manuel,
Arrabal Miguel,
MagánFernández Antonio,
Mesa Francisco
Publication year - 2018
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12909
Subject(s) - erectile dysfunction , medicine , chronic periodontitis , logistic regression , confounding , periodontitis , gastroenterology , pathogenesis
Aim To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers and other comorbidities. Methods A case–control study was conducted on 158 male patients; 80 cases with erectile dysfunction according to the International Index of Erectile Function and 78 controls. Sociodemographic data were gathered, and a periodontal examination was performed. Testosterone, lipid profile, C‐reactive protein and glycaemic parameters were assessed. All variables were compared between groups, and multivariate logistic regression analyses were performed. Results 74% of the cases were diagnosed with chronic periodontitis. Number of sites with pocket probing depth 4‐6 mm ( p = 0.05) and number of sites with clinical attachment loss >3 mm ( p < 0.01) were higher in the cases. Triglycerides ( p < 0.01), C‐reactive protein ( p = 0.02) and glycosylated haemoglobin ( p = 0.04) were also higher in the cases. Logistic regression showed that patients with chronic periodontitis were more likely to have erectile dysfunction ( OR =2.17; 95% CI (1.06–4.43); p = 0.03) independently of other confounders. Conclusion Patients with erectile dysfunction showed worse periodontal condition. Chronic periodontitis seems to play a key role as a risk factor in the pathogenesis of erectile dysfunction independently of other morbidities.