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A systematic review and meta‐analysis of epidemiologic observational evidence on the effect of periodontitis on diabetes An update of the EFP ‐ AAP review
Author(s) -
Graziani Filippo,
Gennai Stefano,
Solini Anna,
Petrini Morena
Publication year - 2018
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12837
Subject(s) - observational study , periodontitis , medicine , diabetes mellitus , incidence (geometry) , gestational diabetes , systematic review , type 2 diabetes , strengthening the reporting of observational studies in epidemiology , medline , dentistry , intensive care medicine , endocrinology , pregnancy , gestation , physics , biology , political science , law , optics , genetics
Aim To update the available evidence on the impact of periodontitis on diabetes control, incidence and complications. Methods Observational studies on the effect of periodontitis on diabetes, published after 2012, were identified through electronic databases and hand‐searched journals. Findings were summarized by evidence tables, using PRISMA statement. Quality of the included studies was evaluated through the Newcastle Ottawa scale. Results Healthy individuals with periodontitis exhibit a poor glycaemic control and a higher risk of developing diabetes. Individuals affected by diabetes show a deterioration of glycaemic control if also affected by periodontitis and significantly higher prevalence of diabetes‐related complications. Limited evidence is available on gestational diabetes and type 1 diabetes. Conclusions Periodontitis has a significant impact on diabetes control, incidence and complications. Nevertheless, the heterogeneity and quality of the included publications suggest that caution should be exercised when interpreting the data and that there remains an important need for additional evidence.