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An update of the evidence on the potential impact of periodontal therapy on diabetes outcomes
Author(s) -
Madianos Phoebus N.,
Koromantzos Panagiotis A.
Publication year - 2018
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12836
Subject(s) - medicine , diabetes mellitus , meta analysis , randomized controlled trial , clinical significance , dentistry , statistical significance , endocrinology
Abstract Aim To provide an update of the systematic review by Engebretson and Kocher J Clin Periodontol. 2013 Apr;40 Suppl 14:S153 on the effect of periodontal therapy on glycaemic control of people with diabetes. Methods PubMed Literature search restricted to meta‐analyses published from 2013 to the present was conducted. The search resulted in seven meta‐analyses of RCT s. Results Reduction in HbA1c at 3–4 months was reported in all reviews for the treatment group ranging from −0.27% (95% CI : −0.46, −0.07, p = .007) to −1.03% (95% CI: 0.36, −1.70, p = 0.003). At 6 months post‐treatment, an HbA1c reduction ranging from −0.02 (95% CI : −0.20, −0.16, p = .84) to −1.18% (95% CI: 0.72%, 1.64%, p < 0.001) was reported. Clinical relevance The magnitude of the reduction in HbA1c, which is found to be associated with non‐surgical periodontal treatment in patients with diabetes, seems to have clinically significant effects on systemic health, and thus should have a place in the treatment of diabetic patients. Conclusions Periodontal treatment ( SRP ) results in a statistically significant reduction in HbA1C levels at 3 months, with a lower reduction at 6 months.