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Natural history of periodontitis: Disease progression and tooth loss over 40 years
Author(s) -
Ramseier Christoph A.,
Anerud Age,
Dulac Mary,
Lulic Martina,
Cullinan Mary P.,
Seymour Gregory J.,
Faddy Malcolm J.,
Bürgin Walter,
Schätzle Marc,
Lang Niklaus P.
Publication year - 2017
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12782
Subject(s) - tooth loss , periodontitis , medicine , gingivitis , dentition , dentistry , clinical attachment loss , cohort , logistic regression , natural history , calculus (dental) , oral health
Objectives To assess long‐term attachment and periodontitis‐related tooth loss (PTL) in untreated periodontal disease over 40 years. Material and Methods Data originated from the natural history of periodontitis study in Sri Lankan tea labourers first examined in 1970. In 2010, 75 subjects (15.6%) of the original cohort were re‐examined. Results PTL over 40 years varied between 0 and 28 teeth (mean 13.1). Four subjects presented with no PTL, while 12 were edentulous. Logistic regression revealed attachment loss as a statistically significant covariate for PTL ( p < .004). Markov chain analysis showed that smoking and calculus were associated with disease initiation and that calculus, plaque, and gingivitis were associated with loss of attachment and progression to advanced disease. Mean attachment loss <1.81 mm at the age of 30 yielded highest sensitivity and specificity (0.71) to allocate subjects into a cohort with a dentition of at least 20 teeth at 60 years of age. Conclusions These results highlight the importance of treating early periodontitis along with smoking cessation, in those under 30 years of age. They further show that calculus removal, plaque control, and the control of gingivitis are essential in preventing disease progression, further loss of attachment and ultimately tooth loss.