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Effect of surgical periodontal treatment associated to antimicrobial photodynamic therapy on chronic periodontitis: A randomized controlled clinical trial
Author(s) -
Martins Sérgio H. L.,
Novaes Arthur B.,
Taba Mario,
Palioto Daniela B.,
Messora Michel R.,
Reino Danilo M.,
Souza Sérgio L. S.
Publication year - 2017
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12744
Subject(s) - medicine , photodynamic therapy , chronic periodontitis , dentistry , antimicrobial , gingival and periodontal pocket , randomized controlled trial , debridement (dental) , periodontitis , treponema denticola , clinical trial , periodontology , gastroenterology , microbiology and biotechnology , porphyromonas gingivalis , chemistry , organic chemistry , biology
Aim This randomized controlled clinical trial evaluated the effects of an adjunctive single application of antimicrobial photodynamic therapy ( aPDT ) in Surgical Periodontal Treatment ( ST ) in patients with severe chronic periodontitis ( SCP ). Material and Methods In a split‐mouth design, 20 patients with SCP were treated with aPDT + ST (Test Group, TG ) or ST only (Control Group, CG ). aPDT was applied in a single episode, using a diode laser and a phenothiazine photosensitizer. All patients were monitored until 90 days after surgical therapy. Levels of 40 subgingival species were measured by checkerboard DNA ‐ DNA hybridization at baseline, 60 and 150 days. Clinical and microbiological parameters were evaluated. Results In deep periodontal pockets depth ( PPD ≥5 mm), Test Group presented a significantly higher decrease in PPD than Control Group at 90 days after surgical therapy ( p < .05). Test Group also demonstrated significantly less periodontal pathogens of red complex ( Treponema denticola ) ( p < .05). Conclusion A single episode of aPDT used in adjunct to open flap debridement of the root surface in the surgical treatment of SCP : i) significantly improved clinical periodontal parameters; ii) eliminates periodontal pathogens of the red complex more effectively ( NCT 02734784).