Long‐term results of periodontal regenerative therapy: A retrospective practice‐based cohort study

Aim Evaluation of the long‐term effectiveness of regenerative treatment of intra‐bony defects in periodontal practice. Material and Methods A total of 1,008 intra‐bony defects in 176 patients were analysed after using collagen‐added deproteinized bovine bone mineral ( DBBM c) with or without collagen membrane ( CM ) or enamel matrix derivative ( EMD ). Defects were classified as one‐ and two‐wall and as shallow (≤6 mm), moderate (>6 and <11 mm) and deep (≥11 mm). Radiographic bone level changes were evaluated after 1 year, 2 to 4 years and 5 to 10 years. Results Mean radiographic defect fill was 3.8 mm after 1 year and remained stable up to 10 years. Deep and moderate defects showed a higher degree of fill than shallow defects (53.3%, 49.2%, 42.9%). Tooth loss amounted to 2.6%, was dependent on initial defect size (1.2% shallow, 1.4% moderate, 5.7% deep defects) and occurred mainly due to endodontic reasons. Conclusions Within the limits of the retrospective study design, the findings indicate that periodontal treatment using DBBM c with or without CM or EMD can lead to long‐term defect reduction and tooth survival for up to 10 years in the setting of a periodontal practice.