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Assessment of arterial stiffness in periodontitis using a novel pulse wave imaging methodology
Author(s) -
SanzMiralles Elena C.,
Li Ronny,
MomenHeravi Fatemeh,
Mendieta Carlos,
Konofagou Elisa E.,
Papapanou Panos N.
Publication year - 2017
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12717
Subject(s) - periodontitis , arterial stiffness , pulse wave velocity , medicine , cardiology , body mass index , dentistry , orthodontics , blood pressure
Aim We investigated the cross‐sectional relationship between periodontal status and arterial stiffness, assessed through a novel Pulse Wave Imaging methodology. Methods Eighty volunteers were enrolled (39% male, age range 24–78 years) and 33 pairs were formed of periodontitis patients/periodontally healthy controls, matched by age and gender. A full‐mouth periodontal examination was performed and the degree of stiffness of the right and left carotid arteries was assessed by measuring pulse wave velocity ( PWV ) and the uniformity in pulse wave propagation ( R 2 ). Wilcoxon signed‐rank tests for paired observations were used to compare periodontitis patients and healthy controls. Univariate and multivariate analyses were performed to analyze the association between PWV and R 2 and potential explanatory variables. Results Patients with periodontitis had a statistically significantly lower uniformity in wave propagation ( R 2 ) than controls ( p = .01), but PWV did not differ between the two groups. Univariate analysis showed a significant negative association between R 2 and periodontitis, body mass index and smoking; periodontitis remained statistically associated with R 2 in the multivariate analyses. Conclusions Patients with periodontitis and no established cardiovascular disease presented with lower degree of uniformity in the transmission of the pulse wave through the carotid arteries, suggesting an association between periodontitis and arterial stiffness/functional alterations.