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Evaluation of the adjunctive effect of platelet‐rich fibrin to enamel matrix derivative in the treatment of intrabony defects. Six‐month results of a randomized, split‐mouth, controlled clinical study
Author(s) -
Aydemir Turkal Humerya,
Demirer Serhat,
Dolgun Anil,
Keceli Huseyin Gencay
Publication year - 2016
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12598
Subject(s) - enamel matrix derivative , platelet rich fibrin , dentistry , medicine , enamel paint , fibrin , randomized controlled trial , orthodontics , surgery , biology , regeneration (biology) , immunology , microbiology and biotechnology
Aim This study aimed to compare the results obtained with enamel matrix derivative ( EMD ) and EMD + platelet‐rich fibrin ( PRF ) in the treatment of intrabony defects ( IBD s) in chronic periodontitis patients. Materials and Methods Using a split‐mouth design, 28 paired IBD s were randomly treated either with EMD or with EMD + PRF . Clinical and radiographic measurements including clinical attachment level ( CAL ), probing depth ( PD ), gingival recession ( GR ), defect depth ( DD ), defect width ( DW ) and defect angle ( DA ) were recorded at baseline ( BL ) and at six months following therapy. Results BL clinical and radiographic measurements were similar for EMD and EMD + PRF groups. Although postsurgical measurements revealed significant reduction for PD and CAL in both groups, no intergroup difference was detected. When EMD and EMD + PRF groups were compared, defect fill was not also statistically different. Conclusions Both therapies resulted in significant clinical improvement in IBD treatment. Addition of PRF did not improve the clinical and radiographic outcomes.