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Alcohol consumption and risk of periodontitis: a meta‐analysis
Author(s) -
Wang Jiantao,
Lv Jian,
Wang Wanchun,
Jiang Xiubo
Publication year - 2016
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12556
Subject(s) - meta analysis , periodontitis , medicine , relative risk , confidence interval , observational study , alcohol consumption , cohort study , dentistry , subgroup analysis , alcohol , environmental health , biology , biochemistry
Abstract Aim A meta‐analysis was conducted to quantitatively summarize the evidence from observational studies on alcohol consumption and risk of periodontitis. Material and Methods A comprehensive literature search was performed in PubMed, Web of Science and Embase databases to identify eligible studies published in English. Pooled relative risks ( RR s) with 95% confidence intervals ( CI s) were calculated by random‐effects models. Restricted cubic splines were used to assess the dose–response relationship. Results Eighteen studies were included in our meta‐analysis. The pooled RR of periodontitis for the highest with the lowest alcohol consumption was 1.59 (95% CI : 1.37–1.85). Significant associations were also found in stratified analysis by gender [males: (1.25, 95% CI : 1.11–1.41), females (2.15, 95% CI : 1.36–3.41)] and study design [cohort studies: 1.28 (1.04–1.57) and cross‐sectional studies: 1.66 (1.39–1.99)]. A linear dose–response relationship was found between alcohol consumption and periodontitis risk, and the risk of periodontitis increased by 0.4% [95% CI (1.002–1.007) ( p = 0.002)] for each 1 g/day increment in alcohol consumption. Conclusion This meta‐analysis suggested that alcohol consumption was associated with an increased risk of periodontitis.