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The JP 2 genotype of Aggregatibacter actinomycetemcomitans and marginal periodontitis in the mixed dentition
Author(s) -
Jensen Anne Birkeholm,
Ennibi Oum Keltoum,
Ismaili Zouheir,
Poulsen Knud,
Haubek Dorte
Publication year - 2016
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12486
Subject(s) - aggregatibacter actinomycetemcomitans , genotype , periodontitis , clinical attachment loss , dentition , medicine , dentistry , aggressive periodontitis , bleeding on probing , gingivitis , biology , genetics , porphyromonas gingivalis , gene
Aim To perform a cross‐sectional study on the carrier frequency of JP 2 and non‐ JP 2 genotypes of A. actinomycetemcomitans in Moroccan school children and relate the presence of these genotypes to the periodontal status in the mixed dentition. Material and Methods A plaque sample from 513 children was analysed by PCR . JP 2 genotype‐positive subjects ( n = 46), an equally sized group of non‐ JP 2 genotype‐positive subjects, and an A. actinomycetemcomitans ‐negative group were randomly chosen among the remaining subjects for clinical and radiographic examination. Results Among 513 children, 46 (9.0%) carried the JP 2 genotype and 186 (36.3%) were positive for non‐ JP 2 genotypes , whereas A. actinomycetemcomitans could not be detected in the remaining 281 subjects. Among 75 subjects with mixed dentition and selected for clinical examination, clinical attachment loss ( CAL ) ≥3 mm at two or more periodontal sites on primary teeth was found in the JP 2 genotype‐positive group only. In total, 6.7% of subjects with primary teeth present showed CAL ≥3 mm at two or more sites. Conclusions The carrier frequency of the JP 2 genotype of A. actinomycetemcomitans was at a comparable level to frequencies previously found in Moroccan adolescent populations. Clinical attachment loss, manifesting already in the primary dentition, was found only in the group of Moroccan children carrying the JP 2 genotype of A. actinomycetemcomitans .