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Effects of non‐equilibrium plasma in the treatment of ligature‐induced peri‐implantitis
Author(s) -
Shi Qi,
Song Ke,
Zhou Xincai,
Xiong Zilan,
Du Tianfeng,
Lu Xinpei,
Cao Yingguang
Publication year - 2015
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12403
Subject(s) - peri implantitis , tannerella forsythia , ligature , dentistry , medicine , porphyromonas gingivalis , beagle , periodontitis , debridement (dental) , chlorhexidine , implant , surgery , pathology , traditional chinese medicine , honeysuckle , alternative medicine
Aim To evaluate the effects of non‐equilibrium plasma in the treatment of ligature‐induced peri‐implantitis in beagle dogs. Materials and Methods Six beagles received 12 implants installed in the position of the fourth mandibular premolars. Ligature‐induced peri‐implantitis was initiated at 3 months post‐implantation. When approximately 40% of the supporting bone was lost, the ligatures were removed. The implants were subjected to the muco‐periosteal scaling and chlorhexidine irrigation with or without plasma irrigation. Three months later, clinical, radiographic and microbiological analyses were performed. Block biopsies were prepared for micro‐ CT and histomorphometric analysis. The primary outcome was the difference in bone healing of peri‐implant sites, and the secondary outcomes included changes in clinical parameters ( SBI , PD ) and bacterial detection. Results At baseline, no significant differences were observed between the two groups. At 3 months post‐treatment, the plasma group showed a significantly higher bone level than the control group ( p < 0.05), a significantly decreased detection of bacteria ( Porphyromonas gingivalis and Tannerella forsythia ) ( p < 0.05), and a significant improvement in clinical examination ( p < 0.05). Conclusions Within the limits of this study, non‐equilibrium plasma treatment as an adjunct to the conventional therapy is a feasible approach for the treatment of peri‐implantitis.