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Effects of periodontal treatment on lung function and exacerbation frequency in patients with chronic obstructive pulmonary disease and chronic periodontitis: A 2‐year pilot randomized controlled trial
Author(s) -
Zhou Xuan,
Han Jing,
Liu Zhiqiang,
Song Yiqing,
Wang Zuomin,
Sun Zheng
Publication year - 2014
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12247
Subject(s) - medicine , copd , exacerbation , randomized controlled trial , periodontitis , chronic periodontitis , oral hygiene , pulmonary function testing , scaling and root planing , vital capacity , pulmonary disease , physical therapy , dentistry , lung function , lung , diffusing capacity
Abstract Aim To evaluate the direct effects of periodontal therapy in C hronic O bstructive P ulmonary D isease ( COPD ) patients with chronic periodontitis ( CP ). Materials and Methods In a pilot randomized controlled trial, 60 COPD patients with CP were randomly assigned to receive scaling and root planing ( SRP ) treatment, supragingival scaling treatment, or oral hygiene instructions only with no periodontal treatment. We evaluated their periodontal indexes, respiratory function, and COPD exacerbations at baseline, 6 months, 1, and 2 years. Results Compared with the control group, measurements of periodontal indexes were significantly improved in patients in two treatment groups at 6‐month, 1‐year, and 2‐year follow‐up (all p < 0.05). Overall, the means of forced expiratory volume in the first second/forced vital capacity ( FEV 1/ FVC ) and FEV 1 were significantly higher in the two therapy groups compared with the control group during the follow‐up ( p < 0.05). In addition, the frequencies of COPD exacerbation were significantly lower in the two therapy groups than in the control group at 2‐year follow‐up ( p < 0.05). Conclusions Our preliminary results from this pilot trial suggest that periodontal therapy in COPD patients with CP may improve lung function and decrease the frequency of COPD exacerbation.