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Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo‐controlled study
Author(s) -
Teughels Wim,
Durukan Andaç,
Ozcelik Onur,
Pauwels Martine,
Quirynen Marc,
Haytac Mehmet Cenk
Publication year - 2013
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12155
Subject(s) - lactobacillus reuteri , scaling and root planing , medicine , probiotic , placebo , chronic periodontitis , lozenge , periodontitis , randomized controlled trial , gastroenterology , porphyromonas gingivalis , dentistry , bacteria , biology , pathology , history , genetics , alternative medicine , archaeology
Aim The aim of this randomized placebo‐controlled clinical trial was to evaluate the effects of Lactobacillus reuteri‐ containing probiotic lozenges as an adjunct to scaling and root planing ( SRP ). Material and Methods Thirty chronic periodontitis patients were recruited and monitored clinically and microbiologically at baseline, 3, 6, 9 and 12 weeks after therapy. All patients received one‐stage full‐mouth disinfection and randomly assigned over a test ( SRP + probiotic, n = 15) or control ( SRP + placebo, n = 15) group. The lozenges were used two times a day for 12 weeks. Results At week 12, all clinical parameters were significantly reduced in both groups, while there was significantly more pocket depth reduction ( p < 0.05) and attachment gain ( p < 0.05) in moderate and deep pockets; more Porphyromonas gingivalis reduction was observed in the SRP + probiotic group. Conclusions The results indicate that oral administration of L. reuteri lozenges could be a useful adjunct to SRP in chronic periodontitis.