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Treatment of gingival recession defects with a coronally advanced flap and a xenogeneic collagen matrix: a multicenter randomized clinical trial
Author(s) -
Jepsen Karin,
Jepsen Søren,
Zucchelli Giovanni,
Stefanini Martina,
Sanctis Massimo,
Baldini Nicola,
Greven Björn,
Heinz Bernd,
Wennström Jan,
Cassel Björn,
Vignoletti Fabio,
Sanz Mariano
Publication year - 2013
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12019
Subject(s) - medicine , gingival recession , dentistry , randomized controlled trial , surgery
Aim To evaluate the clinical outcomes of the use of a xenogeneic collagen matrix ( CM ) in combination with the coronally advanced flap ( CAF ) in the treatment of localized recession defects. Material & Methods In a multicentre single‐blinded, randomized, controlled, split‐mouth trial, 90 recessions (Miller I, II) in 45 patients received either CAF + CM or CAF alone. Results At 6 months, root coverage (primary outcome) was 75.29% for test and 72.66% for control defects ( p = 0.169), with 36% of test and 31% of control defects exhibiting complete coverage. The increase in mean width of keratinized tissue ( KT ) was higher in test (from 1.97 to 2.90 mm) than in control defects (from 2.00 to 2.57 mm) ( p = 0.036). Likewise, test sites had more gain in gingival thickness ( GT ) (0.59 mm) than control sites (0.34 mm) ( p = 0.003). Larger (≥3 mm) recessions ( n = 35 patients) treated with CM showed higher root coverage (72.03% versus 66.16%, p = 0.043), as well as more gain in KT and GT . Conclusions CAF + CM was not superior with regard to root coverage, but enhanced gingival thickness and width of keratinized tissue when compared with CAF alone. For the coverage of larger defects, CAF + CM was more effective.