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Chronic periodontitis and the subsequent risk of trigeminal neuralgia: a 5‐year follow‐up study
Author(s) -
Keller Joseph J.,
Sheu JauJiuan,
Lin HerngChing
Publication year - 2012
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1111/jcpe.12003
Subject(s) - medicine , trigeminal neuralgia , cohort , periodontitis , hazard ratio , incidence (geometry) , population , chronic periodontitis , cohort study , dentistry , surgery , confidence interval , physics , environmental health , optics
Aim This study set out to explore the possibility that chronic periodontitis ( CP ) may also be a condition that could potentially result in secondary or symptomatic trigeminal neuralgia ( TN ) by utilizing a population‐based dataset and cohort study design in Taiwan. Materials and Methods We included 110,104 subjects with CP in our study cohort, and randomly selected 110,104 subjects without a history of CP as a comparison cohort. We individually tracked each patient in this study for a 5‐year period to identify those who received a subsequent diagnosis of TN . Results The incidence rate of TN during the 5‐year follow‐up period was 4.40 (95% CI = 3.87–4.98) per 10,000 person‐years for subjects with CP , and 2.60 (95% CI = 2.20‐3.05) per 10,000 person‐years in comparison subjects. Cox proportional analysis revealed that the adjusted hazard ratio ( HR ) of TN during the 5‐year follow‐up period for subjects with CP was 1.65 (95% CI = 1.34–2.03) times higher than that of comparison subjects. However, the study subjects who had undergone a gingivectomy or periodontal flap operation did not have a higher adjusted risk of TN than comparison subjects ( HR = 0.93, 95% CI = 0.54–1.61). Conclusion Our study detected a greater risk for TN among patients with CP than matched comparison subjects .