Open AccessRecent advances on the roles of LncRNAs in cardiovascular disease
Author(s) -
Fang Yexian,
Xu Yuerong,
Wang Runze,
Hu Lang,
Guo Dong,
Xue Feng,
Guo Wangang,
Zhang Dongwei,
Hu Jianqiang,
Li Yan,
Zhang Wei,
Zhang Mingming
Publication year - 2020
Publication title -
journal of cellular and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.44
H-Index - 130
eISSN - 1582-4934
pISSN - 1582-1838
DOI - 10.1111/jcmm.15880
Subject(s) - disease , myocardial infarction , pathological , bioinformatics , myocardial hypertrophy , heart failure , cardiac hypertrophy , medicine , biology , muscle hypertrophy
Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselves. LncRNAs play key roles in the occurrence and development of myocardial infarction, heart failure, myocardial hypertrophy, arrhythmias and other pathological processes that significantly affect the prognosis and survival of patients with cardiovascular diseases. We here review the latest research on lncRNAs in cardiovascular diseases as a basis to formulate future research on prevention and treatment of cardiovascular diseases.