Open AccessTelocytes in mice bone marrow: electron microscope evidence
Author(s) -
Li Hua,
Zhang Hongqi,
Yang Lin,
Lu Shanshan,
Ge Junbo
Publication year - 2014
Publication title -
journal of cellular and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.44
H-Index - 130
eISSN - 1582-4934
pISSN - 1582-1838
DOI - 10.1111/jcmm.12337
Subject(s) - bone marrow , electron microscope , ultrastructure , scanning electron microscope , pathology , transmission electron microscopy , anatomy , chemistry , materials science , biology , medicine , physics , optics , nanotechnology , composite material
Telocytes ( TC s) are a novel type of interstitial cell of whom presence has been recently documented in many tissues and organs. However, whether TC s exists in bone marrow is still not reported. This study aims to find out TC s in mice bone marrow by using scanning electron microscope ( SEM ) and transmission electron microscope ( TEM ). SEM images showed that in mice bone marrow most of TC s have small spherical cell body (usually 4–6 μm diameter) with thin long telopodes (Tps; usually one to three). The longest Tp observed was about 70 μm, with an uneven calibre. Direct intercellular contacts exist between TC s. TEM shows mitochondria within dilations of Tps. Also, by TEM , we show the close spatial relations of Tps with blood vessels. In conclusion, this study provides ultrastructural evidence regarding the existence of TC s in mice bone marrow, in situ .