Open AccessSleep duration and 24‐hour ambulatory blood pressure in adults not on antihypertensive medications
Author(s) -
Shulman Rachel,
Cohen Debbie L.,
Grandner Michael A.,
Gislason Thorarinn,
Pack Allan I.,
Kuna Samuel T.,
Townsend Raymond R.,
Cohen Jordana B.
Publication year - 2018
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.13416
Subject(s) - medicine , blood pressure , ambulatory blood pressure , ambulatory , cardiology , obstructive sleep apnea , sleep apnea , sleep (system call) , apnea , computer science , operating system
Short sleep duration has been widely linked to increased cardiovascular morbidity and mortality. We performed a post hoc analysis of 24‐hour ambulatory blood pressure monitoring (ABPM) in the Lifestyle Modification in Blood Pressure Lowering Study (LIMBS) and Penn Icelandic Sleep Apnea (PISA) Study. The 24‐hour mean systolic blood pressure (BP) was 12.7 mm Hg higher in LIMBS ( P < 0.001; n = 66) and 4.7 mm Hg higher in PISA ( P = 0.005; n = 153) among participants with shorter sleep duration (less than 7 hours) compared to those with longer sleep duration (at least 7 hours). In multivariable adjusted models, shorter sleep duration was strongly associated with higher systolic BP on 24‐hour ABPM, independent of nocturnal BP and in‐office BP. There was no effect modification by obstructive sleep apnea. Adults with shorter sleep duration may benefit from screening with 24‐hour ABPM to promote earlier detection of hypertension and potentially mitigate their increased risk for future cardiovascular disease.