Open AccessAmbulatory blood pressure in relation to oxygen desaturation index as simultaneously assessed by nighttime finger pulse oximetry at home
Author(s) -
Chen Qi,
Cheng YiBang,
Liu ChangYuan,
Guo QianHui,
Xu ShaoKun,
Huang QiFang,
Sheng ChangSheng,
Shen Meng,
Zhu YaJing,
Li Yan,
Wang JiGuang
Publication year - 2018
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.13254
Subject(s) - medicine , pulse oximetry , ambulatory , ambulatory blood pressure , blood pressure , heart rate , pulse (music) , anesthesia , pulse rate , cardiology , diastole , electrical engineering , detector , engineering
We investigated the relationship between ambulatory blood pressure (BP) and oxygen desaturation index (ODI), while accounting for pulse rate and age. ODI was assessed by overnight finger pulse oximetry in 2342 participants on the day of ambulatory BP monitoring, and calculated as the number of desaturation episodes per sleeping hour. Both BP and pulse rate increased significantly ( P ≤ .006) from normal (< 5 events/h) to mildly (5‐14), moderately (15‐30), and severely (≥ 30 events/h) elevated ODI. The association for BP was substantially attenuated by accounting for pulse rate (partial r ² from .003‐.012 to .002‐.006). In adjusted analysis, the associations of 24‐hour diastolic BP and 24‐hour pulse rate with ODI were dependent on age ( P ≤ .0001) and only significant in younger subjects (< 60 years, P ≤ .0001). In conclusion, the association between ambulatory BP and ODI was partially mediated by pulse rate, a measure of sympathetic activity, and was more prominent in younger subjects.