Open AccessThe association between different features of sleep‐disordered breathing and blood pressure: A cross‐sectional study
Author(s) -
Khoshkish Shayan,
Hohl Mathias,
Linz Benedikt,
Arzt Michael,
Mahfoud Felix,
Baumert Mathias,
Schöpe Jakob,
Böhm Michael,
Linz Dominik
Publication year - 2018
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.13202
Subject(s) - medicine , pulse oximetry , blood pressure , cardiology , body mass index , oxygen saturation , hypoxemia , hypoxia (environmental) , diastole , breathing , pulse pressure , sleep apnea , cross sectional study , anesthesia , oxygen , pathology , chemistry , organic chemistry
Sleep disordered breathing ( SDB ) is highly prevalent in patients with high blood pressure ( BP ). Severity of SDB can be evaluated by the number of apneas and hypopneas per hour ( AHI ) or by measures of hypoxia. The objective of this study was to assess the association between different measures of SDB and BP . In 134 consecutive patients, polygraphy was performed to determine the AHI . Pulse oximetry was used to determine hypoxemic burden (time below 90% oxygen saturation [T90] and hypoxia load [ HL ], representing the integrated area above the curve of desaturation). AHI did not correlate with systolic and diastolic BP or pulse pressure. In contrast, HL correlated with pulse pressure during the day ( P = .01) and night ( P = .0034) before and after adjustment for body mass index. The correlation between systolic BP and HL at night disappeared following adjustment for body mass index. This study generates the hypothesis that nocturnal hypoxemic burden may represent a suitable marker of BP pattern and a potential treatment target in hypertensive patients.