Open AccessRenal artery stenting for atherosclerotic renal artery stenosis identified in patients with coronary artery disease: Does captopril renal scintigraphy predict outcomes?
Author(s) -
Stratigis Spyros,
Stylianou Kostas,
Kyriazis Periklis P.,
Dermitzaki EleftheriaKleio,
Lygerou Dimitra,
Syngelaki Paraskevi,
Stratakis Stavros,
Koukouraki Sophia,
Parthenakis Fragiskos,
Tsetis Dimitrios,
Daphnis Eugene
Publication year - 2018
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.13160
Subject(s) - medicine , captopril , renal artery stenosis , renal artery , coronary artery disease , cardiology , revascularization , renovascular hypertension , renal artery obstruction , angiography , kidney disease , scintigraphy , kidney , radiology , blood pressure , myocardial infarction
The authors evaluated the effectiveness of percutaneous renal revascularization ( PRR ) with stenting for the treatment of atherosclerotic renal artery stenosis ( ARAS ) in patients with coronary artery disease and the usefulness of captopril renal scintigraphy for predicting clinical outcomes after PRR . Sixty‐four consecutive patients, referred for evaluation of suspected ARAS , after coronary angiography, underwent baseline captopril renal scintigraphy followed by renal angiography. Forty‐four patients (68.7%) were diagnosed with a significant ARAS ≥ 60% and were treated with PRR plus medical therapy. Twenty‐four months after PRR , 86.4% and 73.3% of patients showed a hypertension and renal benefit, respectively. Captopril renal scintigraphy positivity had moderate sensitivity and high specificity in predicting a hypertension and renal benefit. In patients with ARAS ≥ 70%, the sensitivity and specificity were 100% for both a hypertension and renal benefit . PRR for ARAS conferred a substantial benefit in patients with a high coronary artery disease burden. Captopril renal scintigraphy was highly accurate in predicting clinical outcomes.