Open AccessAssociation between reduced arterial stiffness and preserved diastolic function of the left ventricle in middle‐aged and elderly patients
Author(s) -
Park KyungTaek,
Kim HackLyoung,
Oh Sohee,
Lim WooHyun,
Seo JaeBin,
Chung WooYoung,
Kim SangHyun,
Kim MyungA,
Zo JooHee
Publication year - 2017
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12968
Subject(s) - medicine , cardiology , arterial stiffness , pulse wave velocity , ventricle , diastole , odds ratio , brachial artery , confidence interval , diastolic function , confounding , ankle , surgery , blood pressure
The aim of this study was to investigate whether arterial stiffness plays a role in retaining normal diastolic function in a middle‐aged and elderly Korean population. A total of 267 patients without documented cardiovascular disease, 50 years and older (mean age, 57.3±6.3 years; 69.8% men) were retrospectively analyzed. All patients underwent both transthoracic echocardiography and brachial‐ankle pulse wave velocity measurement on the same day. Patients with septal annular peak velocity (e’) ≥8 cm/s and left atrial volume index <34 mL /m 2 were considered as having normal diastolic function. Ninety‐eight patients (36.7%) had normal diastolic function. Low brachial‐ankle pulse wave velocity (<1314 cm/s) was an independent factor for determining normal diastolic function even after controlling for potential confounders in multiple logistic regression analysis (odds ratio, 2.58; 95% confidence interval, 1.46–4.57; P =.001). Our results suggest that compliant arteries may play an important role in maintaining normal left ventricular diastolic function in middle‐aged and elderly patients without documented cardiovascular disease.