Open AccessGlucose homeostasis abnormalities among Cameroon patients with newly diagnosed hypertension
Author(s) -
Kamdem Félicité,
Lemogoum Daniel,
Doualla MarieSolange,
Kemta Lepka Fernando,
Temfack Elvis,
Ngo Nouga Yvette,
Kenmegne Caroline,
Luma Henry,
Hermans Michel P
Publication year - 2017
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12959
Subject(s) - medicine , glucose homeostasis , odds ratio , diabetes mellitus , confidence interval , homeostasis , blood pressure , logistic regression , endocrinology , gastroenterology , insulin resistance
The authors assessed the frequency of glucose homeostasis abnormalities among 839 Cameroonians with newly diagnosed hypertension (mean age: 50.8±11 years; 49.9% female) in a cross‐sectional survey conducted at the Douala General Hospital, Douala, Cameroon. In all participants, blood pressure, fasting plasma glucose ( FPG ), and lipids were recorded. Impaired fasting glycemia was described as an FPG level between 100 and 125 mg/dL and provisional diabetes as an FPG level ≥126 mg/dL. The FPG was 101±30 mg/dL. The overall proportion of abnormal glucose homeostasis was 38.3%, while 7.7% of patients (n=65) had known diabetes. A total of 23.7% (n=199) had impaired fasting glycemia and 6.8% (n=57) had provisional diabetes. Multivariable logistic regression revealed that male sex (odds ratio [OR], 1.53; 95% confidence interval [CI], 1.15–2.06), age older than 55 years ( OR , 1.55; 95% CI , 1.15–2.09), and low‐density lipoprotein cholesterol >1 g/L ( OR , 1.34; 95% CI , 1.00–1.82) were independently associated with abnormal glucose homeostasis (all P <.05). Glucose homeostasis abnormalities are highly prevalent among Cameroonian patients with newly diagnosed hypertension.