Open AccessNovel Triggered Nocturnal Blood Pressure Monitoring for Sleep Apnea Syndrome: Distribution and Reproducibility of Hypoxia‐Triggered Nocturnal Blood Pressure Measurements
Author(s) -
Kuwabara Mitsuo,
Hamasaki Haruna,
Tomitani Naoko,
Shiga Toshikazu,
Kario Kazuomi
Publication year - 2017
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12878
Subject(s) - nocturnal , medicine , hypoxia (environmental) , blood pressure , sleep apnea , apnea , repeatability , cardiology , circadian rhythm , reproducibility , anesthesia , oxygen , chemistry , organic chemistry , chromatography
Obstructive sleep apnea (OSA) causes blood pressure (BP) surges during sleep, which may lead to increased sleep‐onset cardiovascular events. The authors recently developed a triggered nocturnal BP monitoring system that initiates BP measurements when oxygen desaturation falls below a variable threshold. The distribution and reproducibility of hypoxia‐triggered nocturnal BP parameters compared with those of fixed‐interval nocturnal BP parameters for two consecutive nights in 147 OSA patients (mean age 59.4 years, 86.4% men) were evaluated. The mean and distribution (standard deviation [SD]) of the hypoxia‐peak systolic BP (SBP) were significantly greater than that of the mean nocturnal SBP (mean±SD: 148.8±20.5 vs 123.4±14.2 mm Hg, P <.001). The repeatability coefficient (expressed as %MV) of hypoxia‐peak SBP between night 1 and night 2 was comparable to that of mean nocturnal SBP (43% vs 32%). In conclusion, hypoxia‐peak nocturnal BP was much higher than mean nocturnal BP, and it was as reproducible as mean nocturnal BP.