Bone Mineral Density Is Negatively Associated With Arterial Stiffness in Men With Hypertension

Hypertension ( HTN ) and osteoporosis are associated with the development and progress of atherosclerosis. However, little research has been conducted to examine the relationship between arterial stiffness and bone mineral density ( BMD ) in men with HTN . This cross‐sectional study recruited 355 men with HTN and 353 control patients without HTN . Brachial‐ankle pulse wave velocity (ba PWV ) and BMD measurements were performed. BMD was decreased and ba PWV was elevated in patients with HTN compared with control patients (femoral neck [ FN ] BMD in the HTN and control groups were 0.662±0.195 g/cm 2 and 0.713±0.204 g/cm 2 , respectively [ P =.001], and ba PWV in the HTN and control groups were 1403.3±156.8 cm/s and 1354.8±136.0 cm/s, respectively [ P <.001]). Multiple linear regression analysis demonstrated that FN BMD was negatively associated with increased ba PWV in HTN . Reduced FN BMD may be an independent factor for ba PWV in patients with HTN .