Open AccessDo Combined Electrocardiographic and Echocardiographic Markers of Left Ventricular Hypertrophy Improve Cardiovascular Risk Estimation?
Author(s) -
Cuspidi Cesare,
Facchetti Rita,
Sala Carla,
Bombelli Michele,
Tadic Marijana,
Grassi Guido,
Mancia Giuseppe
Publication year - 2016
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12834
Subject(s) - medicine , left ventricular hypertrophy , cardiology , electrocardiography , muscle hypertrophy , estimation , blood pressure , management , economics
The authors estimated the risk of cardiovascular mortality associated with echocardiographic ( ECHO ) left ventricular hypertrophy ( LVH ) and subtypes of this phenotype in patients with and without electrocardiographic ( ECG ) LVH . A total of 1691 representatives of the general population were included in the analysis. During a follow‐up of 211 months, 89 cardiovascular deaths were recorded. Compared with individuals with neither ECHO LVH nor ECG LVH , fully adjusted risk of cardiovascular mortality increased (hazard ratio [ HR ], 3.36; 95% confidence interval [ CI ], 1.51–7.47; P =.003) in patients with both ECHO ‐ LVH and ECG ‐ LVH , whereas the risk entailed by ECHO ‐ LVH alone was of borderline statistical significance ( P =.04). Combined concentric nondilated LVH and ECG ‐ LVH , but not concentric nondilated LVH alone, predicted cardiovascular death ( HR , 3.79; 95% CI , 1.25–11.38; P =.01). Similar findings were observed for eccentric nondilated LVH ( HR , 3.37; 95% CI , 1.05–10.78; P =.04.). The present analysis underlines the value of combining ECG and ECHO in the assessment of cardiovascular prognosis related to abnormal left ventricular geometric patterns.