Open AccessRiser Pattern: Another Determinant of Heart Failure With Preserved Ejection Fraction
Author(s) -
Komori Takahiro,
Eguchi Kazuo,
Saito Toshinobu,
Hoshide Satoshi,
Kario Kazuomi
Publication year - 2016
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12818
Subject(s) - medicine , cardiology , ejection fraction , heart failure with preserved ejection fraction , heart failure , odds ratio , confidence interval , ambulatory , circadian rhythm , blood pressure , logistic regression , ambulatory blood pressure
Paradoxical increase in blood pressure ( BP ) during sleep, exceeding those of awake BP , is called the “riser” BP pattern, and known as an abnormal circadian BP rhythm, has been reported to be associated with adverse cardiovascular prognoses. However, the significance of ambulatory BP in heart failure patients with preserved ejection fraction ( HF p EF ) has never been reported. Here, we tested our hypothesis that abnormal circadian BP rhythm is associated with HF p EF . The authors enrolled 508 patients with hospitalized HF (age 68±13 years; 315 men, 193 women). There were 232 cases of HF p EF and 276 cases of heart failure with reduced ejection fraction ( HF r EF ). The riser BP pattern was significantly more frequent in the HF p EF (28.9%) group compared with the HF r EF group (19.9%). In a multivariable logistic regression analysis, the riser BP pattern was associated with HF p EF (odds ratio, 1.73; 95% confidence interval, 1.02–2.91; P =.041) independent of the other covariates. In conclusion, the riser BP pattern was associated with HF p EF .