Open AccessAssessment of Left Ventricular Mass and Hypertrophy by Cardiovascular Magnetic Resonance Imaging in Pediatric Hypertension
Author(s) -
SupeMarkovina Katarina,
Nielsen James C.,
Musani Muzammil,
Panesar Laurie E.,
Woroniecki Robert P.
Publication year - 2016
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12808
Subject(s) - medicine , left ventricular hypertrophy , magnetic resonance imaging , cardiology , gold standard (test) , ambulatory blood pressure , cardiac magnetic resonance imaging , echo (communications protocol) , ambulatory , blood pressure , radiology , computer network , computer science
Cardiovascular magnetic resonance ( CMR ) imaging in adults is considered the gold standard for assessment of left ventricular mass ( LVM ) and left ventricular hypertrophy ( LVH ). The authors aimed to evaluate agreement of LVM measurements and LVH determination between echocardiography ( ECHO ) and CMR imaging in children with hypertension ( HTN ) confirmed by 24‐hour ambulatory blood pressure monitoring ( ABPM ). The children (n=22) underwent contemporaneous ECHO , CMR imaging, and ABPM. Patients had a mean body mass index of 30.9±7.5 (kg/m 2 ), and 81.8% had severe HTN . LVM measured by ECHO was 189.6±62.1 g and by CMR imaging was 164.6±44.7 g ( P <.0001). Bland‐Altman analysis revealed significant variability between ECHO and CMR imaging in the measurement of LVM . Interobserver error was higher with ECHO than with CMR imaging. ECHO had high sensitivity and low specificity in LVH determination. In conclusion, ECHO overestimates LVM and is less accurate in measuring LVM as compared with CMR imaging in children with HTN . Further prospective study using CMR imaging to assess LVM in children is warranted.