Open AccessShort‐Term and Long‐Term Reproducibility of Hypertension Phenotypes Obtained by Office and Ambulatory Blood Pressure Measurements
Author(s) -
Sierra Alejandro,
Vinyoles Ernest,
Banegas José R.,
Parati Gianfranco,
Cruz Juan J.,
Gorostidi Manuel,
Segura Julián,
Ruilope Luis M.
Publication year - 2016
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12792
Subject(s) - masked hypertension , medicine , white coat hypertension , ambulatory blood pressure , interquartile range , reproducibility , blood pressure , ambulatory , diastole , cardiology , statistics , mathematics
The authors aimed to assess the reproducibility of normotension and white‐coat, masked, and sustained hypertension in 839 untreated patients who underwent two separate assessments (median, 3; interquartile range, 0–13 months) by both office and ambulatory blood pressure (BP) monitoring ( ABPM ). The proportion of patients falling into the same category in the two assessments was: 52% normotension and 55% white‐coat, 47% masked, and 82% sustained hypertension. The most frequent switch was to sustained hypertension (26% of white‐coat and 33% of masked hypertension). No clinical factors predicted the change in category, except for higher office diastolic BP in patients with masked hypertension who developed sustained hypertension, compared with those who remained with masked hypertension (84±4 mm Hg vs 80±5 mm Hg; P =.006). The reproducibility of hypertension phenotypes was highly dependent on the time between assessments. The authors conclude that white‐coat and masked hypertension phenotypes are only reproducible in the short‐term, while they frequently shift towards sustained hypertension in the long‐term.