Open AccessIs Daytime Systolic Load an Important Risk Factor for Target Organ Damage in Pediatric Hypertension?
Author(s) -
Conkar Seçil,
Yılmaz Ebru,
Hacıkara Şükriye,
Bozabalı Sibel,
Mir Sevgi
Publication year - 2015
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12608
Subject(s) - medicine , pulse wave velocity , cardiology , microalbuminuria , ambulatory blood pressure , blood pressure , diastole , left ventricular hypertrophy , end organ damage , risk factor , ambulatory , pulse pressure
The aim of this study was to compare ambulatory blood pressure (BP) monitoring ( ABPM ) data and determine which hypertension type is a risk factor in target organ damage. A total of 82 children (47 boys) with suspected hypertension based on office BP measurements and considered hypertensive by ABPM were studied . Target organ damage included the following: 35.3% hypertensive retinopathy, 25.6% microalbuminuria, 15.8% increased left ventricular mass index, 29.2% increased carotid intima‐media thickness ( cIMT ), 24.3% high augmentation index (AIx), and 19.5% high pulse wave velocity ( PWV ). The association between BP load, PWV , and cIMT was statistically significant. There were significant correlations between daytime systolic BP load, PWV , AIx , and cIMT . A statistically significant difference was also detected between nighttime systolic BP load, PWV , and cIMT values and nighttime diastolic BP load levels and values of AIx and cIMT . There was also a statistically significant difference between the high level of nighttime diastolic BP load and cIMT . The authors found that target organ damage was seen more often in children with primary hypertension who had systolic loads.