Open AccessIncreased Neutrophil to Lymphocyte Ratio in Patients With Resistant Hypertension
Author(s) -
Belen Erdal,
Sungur Aylin,
Sungur Mustafa Azmi,
Erdoğan Güney
Publication year - 2015
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/jch.12533
Subject(s) - medicine , neutrophil to lymphocyte ratio , absolute neutrophil count , resistant hypertension , ambulatory blood pressure , lymphocyte , etiology , gastroenterology , blood pressure , inflammation , multivariate analysis , ambulatory , immunology , toxicity , neutropenia
Resistant hypertension ( RHT ) is an important disease that causes an increase in cardiovascular risk, yet its etiology remains unclear. The authors aimed to investigate neutrophil/lymphocyte ratio ( NLR ) as an inflammation marker in patients with RHT . A total of 150 patients were included in the study and grouped according to their office and ambulatory blood pressure measurements. They were classified as having normotension ( NT ), controlled hypertension ( CHT ), or RHT . The RHT group had a significantly higher NLR than the CHT group ( P =.03), and NLR s of both hypertension groups were significantly higher than those in the NT group ( P <.001, for both). NLR and neutrophil count were found to be independent correlates for RHT in multivariate analysis ( P <.001). NLR and neutrophil count are increased in RHT patients than both CHT and NT patients. This finding, which is defined for the first time in patients with RHT , may imply the importance of inflammation in blood pressure control.