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Non‐pulmonary vein triggers in nonparoxysmal atrial fibrillation: Implications of pathophysiology for catheter ablation
Author(s) -
Della Rocca Domenico G.,
Tarantino Nicola,
Trivedi Chintan,
Mohanty Sanghamitra,
Anannab Alisara,
Salwan Anu S.,
Gianni Carola,
Bassiouny Mohamed,
AlAhmad Amin,
Romero Jorge,
Briceño David F.,
Burkhardt J. David,
Gallinghouse G. Joseph,
Horton Rodney P.,
Di Biase Luigi,
Natale Andrea
Publication year - 2020
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/jce.14638
Subject(s) - medicine , atrial fibrillation , pulmonary vein , catheter ablation , ablation , cardiology , intensive care medicine , cardiac electrophysiology , population , isolation (microbiology) , bioinformatics , electrophysiology , environmental health , biology
Rhythm control of persistent atrial fibrillation (AF) patients represents a challenge for the modern interventional cardiac electrophysiologist; as a matter of fact, there is still divergence regarding the best ablative approach to adopt in this population. Different investigational endpoints, variability of techniques and tools, significant technological evolution, and the lack of universally accepted pathophysiological models engendered a considerable heterogeneity in terms of techniques and outcomes, so much that the treatment of persistent subtypes of AF commonly still relies mainly on pulmonary vein (PV) isolation. The purpose of the present review is to report the current experimental and clinical evidence supporting the importance of mapping and ablating non‐PV triggers and describe our institutional approach for the ablation of nonparoxysmal AF.