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Comparison of myocardial injury and inflammation after pulmonary vein isolation for paroxysmal atrial fibrillation between radiofrequency catheter ablation and cryoballoon ablation
Author(s) -
Yano Masamichi,
Egami Yasuyuki,
Yanagawa Kyosuke,
Nakamura Hitoshi,
Matsuhiro Yutaka,
Yasumoto Koji,
Tsuda Masaki,
Okamoto Naotaka,
Tanaka Akihiro,
MatsunagaLee Yasuharu,
Yamato Masaki,
Shutta Ryu,
Nishino Masami,
Tanouchi Jun
Publication year - 2020
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/jce.14475
Subject(s) - medicine , pulmonary vein , atrial fibrillation , cardiology , catheter ablation , ablation , radiofrequency ablation , biomarker , inflammation , biochemistry , chemistry
Backgrounds Several studies have shown the serum high sensitive cardiac troponin I (hs‐TnI) a biomarker of myocardium injury, and C‐reactive protein (CRP), a biomarker of inflammation, are associated with worse cardiovascular outcomes. We evaluated the relationship between the hs‐TnI level in patients with paroxysmal atrial fibrillation (PAF) after pulmonary vein isolation (PVI) and atrial fibrillation (AF) recurrence. Methods and Results We enrolled 263 consecutive PAF patients who underwent PVI from May 2017 to April 2018. We investigated the difference in the relationship between the myocardial injury marker (serum hs‐TnI), inflammatory marker (CRP, white blood cell) at 36 to 48 hours after the PVI, and early or late recurrence of AF (ERAF; <3 months and LRAF; from 3 months to 1 year) between the radiofrequency ablation group (R group) and cryoballoon ablation group (C group). The R group consisted of 147 patients and the C groups consisted of 116 patients. The serum hs‐TnI level in R group was significantly lower than in the C group (2.33 vs 5.08 ng/mL; P < .001), while the CRP was significantly higher in the R group than C group (2.02 vs 1.10 mg/dL; P < .001). The incidences of an ERAF/LRAF were similar between the two groups. Conclusion Cryoballoon ablation may cause more myocardial injury than radiofrequency catheter ablation, on the contrary, radiofrequency catheter ablation, may cause more inflammation than cryoballoon ablation. However, these phenomena may not affect the recurrence of AF after the PVI in patient with PAF.