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Permanent His Bundle Pacing: The Past, Present, and Future
Author(s) -
SHARMA PARIKSHIT S.,
ELLENBOGEN KENNETH A.,
TROHMAN RICHARD G.
Publication year - 2017
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/jce.13154
Subject(s) - medicine , cardiac resynchronization therapy , cardiology , bundle , qrs complex , atrial fibrillation , ventricular pacing , ejection fraction , left bundle branch block , heart failure , ventricular function , bundle branch block , electrical conduction system of the heart , electrocardiography , materials science , composite material
Permanent His Bundle Pacing Long‐term right ventricular (RV) apical pacing has been associated with an increased risk of death, heart failure, and atrial fibrillation (AF). Alternative sites for RV pacing have not proven to be superior to RV apical pacing. Cardiac resynchronization therapy (CRT) using a biventricular (BiV) lead system is indicated for patients with a low left ventricular ejection fraction and QRS prolongation, but there remains about a 25–30% nonresponse rate. CRT has been less effective for nonleft bundle branch block conduction delay and with normal/low normal left ventricular function. Over the past decade, there have been more data on the feasibility and advantages of pacing at the His Bundle (HB) region. We review the anatomy and physiology of the HB, the available data on permanent HB pacing, its current and potential future applications.