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Detection of selection signatures for agonistic behaviour in cattle
Author(s) -
Eusebi P.G.,
Cortés O.,
Carleos C.,
Dunner S.,
Cañon J.
Publication year - 2018
Publication title -
journal of animal breeding and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.689
H-Index - 51
eISSN - 1439-0388
pISSN - 0931-2668
DOI - 10.1111/jbg.12325
Subject(s) - biology , domestication , genetics , breed , selection (genetic algorithm) , gene , evolutionary biology , candidate gene , snp , identification (biology) , genotype , computational biology , single nucleotide polymorphism , ecology , artificial intelligence , computer science
Summary The identification of genomic regions including signatures of selection produced by domestication and its subsequent artificial selection processes allows the understanding of the evolution of bovine breeds. Although several studies describe the genomic variability among meat or milk production cattle breeds, there are limited studies orientated towards bovine behavioural features. This study is focused on mapping genomic signatures of selection which may provide insights of differentiation between neutral and selected polymorphisms. Their effects are studied in the Lidia cattle traditionally selected for agonistic behaviour compared with Spanish breeds showing tamed behaviour. Two different approaches, BayeScan and SelEstim, were applied using genotypic 50K SNP BeadChip data. Both procedures detected two genomic regions bearing genes previously related to behavioural traits. The frequencies of the selected allele in these two regions in Lidia breed were opposite to those found in the tamed breeds. In these genomic regions, several putative genes associated with enriched metabolic pathways related to the behavioural development were identified, as neurochondrin gene ( NCDN ) or glutamate ionotropic receptor kainate type subunit 3 ( GRIK 3 ) both located at BTA 3 or leucine‐rich repeat and Ig domain containing 2 ( LINGO 2) and phospholipase A2‐activating protein ( PLAA ) at BTA 8.