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Estimation of inbreeding depression on female fertility in the Finnish Ayrshire population
Author(s) -
Martikainen K.,
Tyrisevä A. M.,
Matilainen K.,
Pösö J.,
Uimari P.
Publication year - 2017
Publication title -
journal of animal breeding and genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.689
H-Index - 51
eISSN - 1439-0388
pISSN - 0931-2668
DOI - 10.1111/jbg.12285
Subject(s) - inbreeding depression , inbreeding , biology , single nucleotide polymorphism , runs of homozygosity , fertility , population , snp , genetics , zoology , genotype , demography , gene , sociology
Summary Single nucleotide polymorphism (SNP) data enable the estimation of inbreeding at the genome level. In this study, we estimated inbreeding levels for 19,075 Finnish Ayrshire cows genotyped with a low‐density SNP panel (8K). The genotypes were imputed to 50K density, and after quality control, 39,144 SNPs remained for the analysis. Inbreeding coefficients were estimated for each animal based on the percentage of homozygous SNPs (F PH ), runs of homozygosity (F ROH ) and pedigree (F PED ). Phenotypic records were available for 13,712 animals including non‐return rate (NRR), number of inseminations (AIS) and interval from first to last insemination (IFL) for heifers and up to three parities for cows, as well as interval from calving to first insemination (ICF) for cows. Average F PED was 0.02, F ROH 0.06 and F PH 0.63. A correlation of 0.71 was found between F PED and F ROH , 0.66 between F PED and F PH and 0.94 between F ROH and F PH . Pedigree‐based inbreeding coefficients did not show inbreeding depression in any of the traits. However, when F ROH or F PH was used as a covariate, significant inbreeding depression was observed; a 10% increase in F ROH was associated with 5 days longer IFL0 and IFL1, 2 weeks longer IFL3 and 3 days longer ICF2 compared to non‐inbred cows.