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Effectiveness of mindfulness‐based intervention on psychotic symptoms for patients with schizophrenia: A meta‐analysis of randomized controlled trials
Author(s) -
Liu YuChen,
Li ILing,
Hsiao FeiHsiu
Publication year - 2021
Publication title -
journal of advanced nursing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 155
eISSN - 1365-2648
pISSN - 0309-2402
DOI - 10.1111/jan.14750
Subject(s) - mindfulness , randomized controlled trial , cochrane library , cinahl , meta analysis , psycinfo , psychological intervention , medicine , schizophrenia (object oriented programming) , medline , psychiatry , intervention (counseling) , anxiety , clinical psychology , physical therapy , political science , law
Aims To evaluate the effects of mindfulness‐based intervention on psychotic symptoms, positive symptoms, negative symptoms, depressive symptoms, anxiety, and rehospitalization. Design A meta‐analysis of randomized controlled trials. Data Sources Medline, Embase, Cochrane Central Register of Controlled Trials, PsycINFO, CINAHL, National Digital Library of Theses and Dissertations in Taiwan, and Airiti Library were searched from their earliest available date up to April 2019. Review Methods The guidelines of the Cochrane Collaboration were followed to report this systematic review. Two authors conducted this meta‐analysis independently. Results Nine randomized controlled trials were included. Meta‐analysis showed that mindfulness‐based intervention significantly decreased psychotic symptoms, positive symptoms, negative symptoms, depressive symptoms, and duration of rehospitalization among patients with schizophrenia, and that the reduction in negative symptoms lasted through short‐term follow‐up. The moderation analysis showed that significantly decreased positive symptoms occurred in the nurse‐led intervention group, while no significant impact was found in the psychologist‐led intervention group. Conclusion The psychotic symptoms of the patients with schizophrenia are improved after mindfulness‐based intervention and the effects on the negative symptoms can be maintained for at least 3 to 6 months. Mindfulness‐based intervention provided by nurses produces more improvements in positive symptoms than intervention provided by psychologists. Impact A growing number of mindfulness‐based interventions have been implemented for patients with schizophrenia, although the effectiveness had not previously been established by meta‐analysis. Mindfulness‐based interventions appear to reduce the symptom severity of schizophrenia patients. Further suggestions for healthcare providers and researchers are provided and discussed.