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The influence of intensive lifestyle intervention on patients with isolated impaired fasting glucose: a meta‐analysis
Author(s) -
Yang XiuJuan,
Zou ShuFang,
Xu Yong,
Li Yi,
Yang ShanShan
Publication year - 2016
Publication title -
journal of advanced nursing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.948
H-Index - 155
eISSN - 1365-2648
pISSN - 0309-2402
DOI - 10.1111/jan.13015
Subject(s) - medicine , meta analysis , body mass index , randomized controlled trial , analysis of variance , impaired fasting glucose , weight loss , random effects model , statistic , cholesterol , impaired glucose tolerance , obesity , insulin resistance , statistics , mathematics
Aim To evaluate the effect of intensive lifestyle intervention on patients with isolated impaired fasting glucose. Background The application of lifestyle intervention to clinical nursing can help improve outcomes of patients with impaired fasting glucose. Design We performed a meta‐analysis of randomized controlled trials using methods outlined in the Cochrane Handbook. Methods We performed keyword searches of the literature databases up to September 2014 and performed manual searches of selected article reference lists. Data were extracted by the lead reviewer, cross‐checked by the second reviewer, entered into RevMan5·3, and pooled and analysed using the fixed effect inverse‐variance model or random effects model to determine the mean difference and calculate the weighted mean difference. The heterogeneity statistic ( I 2 ), overall effect (Z) and P ‐value were calculated. Results A total of five studies were included in our analysis. Following the heterogeneity test statistic, overall effect Z score with P ‐value was calculated. The targets of fasting plasma glucose, weight, body mass index, triglycerides, high‐density lipoprotein cholesterol and total cholesterol all showed significant differences between the intervention and control groups. Conclusion Lifestyle intervention can improve glycaemic control in patients with isolated impaired fasting glucose. It also reduces blood‐lipid levels and promotes weight loss. Larger patient cohorts and adequate follow‐up should be included in future trials.