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Metabolic engineering for isoprenoid‐based biofuel production
Author(s) -
Gupta P.,
Phulara S.C.
Publication year - 2015
Publication title -
journal of applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 1364-5072
DOI - 10.1111/jam.12871
Subject(s) - biofuel , metabolic engineering , biochemical engineering , terpenoid , renewable energy , sustainable production , renewable resource , production (economics) , environmental science , microbiology and biotechnology , engineering , chemistry , biology , ecology , biochemistry , macroeconomics , economics , enzyme
Summary Sustainable economic and industrial growth is the need of the hour and it requires renewable energy resources having better performance and compatibility with existing fuel infrastructure from biological routes. Isoprenoids (C ≥ 5) can be a potential alternative due to their diverse nature and physiochemical properties similar to that of petroleum based fuels. In the past decade, extensive research has been done to utilize metabolic engineering strategies in micro‐organisms primarily, (i) to overcome the limitations associated with their natural and non‐natural production and (ii) to develop commercially competent microbial strain for isoprenoid‐based biofuel production. This review briefly describes the engineered isoprenoid biosynthetic pathways in well‐characterized microbial systems for the production of several isoprenoid‐based biofuels and fuel precursors.