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Surface functionalization of bioactive glasses and hydroxyapatite with polyphenols from organic red grape pomace
Author(s) -
Riccucci Giacomo,
Cazzola Martina,
Ferraris Sara,
Gobbo Virginia Alessandra,
Miola Marta,
Bosso Antonella,
Örlygsson Gissur,
Ng Chuen How,
Verné Enrica,
Spriano Silvia
Publication year - 2022
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/jace.17849
Subject(s) - pomace , surface modification , polyphenol , grafting , chemistry , scavenging , redox , bioactive glass , porosity , chemical engineering , organic chemistry , antioxidant , food science , polymer , engineering
An extract of polyphenols was obtained from organic red grape pomace, chemically analyzed, and used for functionalization of two bioactive glasses and porous hydroxyapatite. Functionalization is effective on hydroxyapatite and the bioactive glass with higher surface reactivity with a different grafting mechanism. Grafting does not inhibit redox and radical scavenging activity of polyphenols. The grafted polyphenols make a continuous layer with an almost complete surface coverage. Polyphenols are released with different kinetics according to the mechanism of grafting and maintain their redox activity. A homogeneous thin layer of polyphenols is still firmly grafted on both substrates after 28 days of soaking and it still maintains radical scavenging activity. The functionalized samples can be sterilized by gamma irradiation.