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New calcium‐free Na 2 O–Al 2 O 3 –P 2 O 5 bioactive glasses with potential applications in bone tissue engineering
Author(s) -
Jeznach Oliwia,
Gajc Marcin,
Korzeb Karolina,
Kłos Andrzej,
Orliński Krzysztof,
Stępień Ryszard,
KrokBorkowicz Małgorzata,
Rumian Łucja,
Pietryga Krzysztof,
Reczyńska Katarzyna,
Pamuła Elżbieta,
Pawlak Dorota A.
Publication year - 2018
Publication title -
journal of the american ceramic society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 196
eISSN - 1551-2916
pISSN - 0002-7820
DOI - 10.1111/jace.15216
Subject(s) - solubility , calcium , quenching (fluorescence) , simulated body fluid , mineralogy , bone tissue , sodium , materials science , nuclear chemistry , chemistry , analytical chemistry (journal) , crystallography , apatite , metallurgy , fluorescence , chromatography , biomedical engineering , physics , quantum mechanics , medicine
Sodium aluminophosphate glasses were evaluated for their bone repair ability. The glasses belonging to the system 45Na 2 O– x Al 2 O 3 ‐(55‐ x )P 2 O 5 , with x = (3, 5, 7, 10 mol%) were prepared by a melt‐quenching method. We assessed the effect of Al 2 O 3 content on the properties of Na 2 O–Al 2 O 3 –P 2 O 5 ( NAP ) glasses, which were characterized by density measurements, DSC analyses, solubility, bioactivity in simulated body fluid and cytocompatibility with MG ‐63 cells. To the best of our knowledge, this is the first investigation of calcium‐free Na 2 O–Al 2 O 3 –P 2 O 5 system glasses as bioactive materials for bone tissue engineering.