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Double dissociation of frontal dysfunction in organic amnesia
Author(s) -
Leng Nicholas R. C.,
Parkin Alan J.
Publication year - 1988
Publication title -
british journal of clinical psychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.479
H-Index - 92
eISSN - 2044-8260
pISSN - 0144-6657
DOI - 10.1111/j.2044-8260.1988.tb00800.x
Subject(s) - wisconsin card sorting test , amnesia , psychology , dissociation (chemistry) , frontal lobe , cognitive disorder , memory disorder , audiology , temporal lobe , developmental psychology , cognition , neuroscience , cognitive psychology , neuropsychology , cognitive impairment , medicine , epilepsy , chemistry
Subjects with either diencephalic or bilateral medial temporal lobe amnesia were examined on the Wisconsin Card Sorting Test (WCST) and Cognitive Estimation Test (CET). Alcoholic Korsakoff patients performed more poorly on the WCST but normally on the CET, whereas post‐encephalitic patients performed normally on the WCST but poorly on the CET. This double dissociation is interpreted as reflecting different patterns of frontal dysfunction in Korsakoff and post‐encephalitic amnesia.

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