Open AccessApplication of orthogonal functions to the spectrophotometric determination of phenytoin in pharmaceutical preparations
Author(s) -
AMER M. M.,
AHMED A. K. S.,
HASSAN S. M.
Publication year - 1977
Publication title -
journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 118
eISSN - 2042-7158
pISSN - 0022-3573
DOI - 10.1111/j.2042-7158.1977.tb11314.x
Subject(s) - phenytoin , chromatography , coefficient of variation , chemistry , dosage form , medicine , epilepsy , psychiatry
A simple ultraviolet spectrophotometric method for the determination of phenytoin in pharmaceutical preparations has been developed. The mean was 100·9% (6 determinations) and the coefficient of variation was 1·2%. The method was applied successfully to the determination of phenytoin in capsules and suspensions.