Open AccessTHE MECHANISM OF HISTAMINE LIBERATION
Author(s) -
Uvnäs Börje
Publication year - 1958
Publication title -
journal of pharmacy and pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.745
H-Index - 118
eISSN - 2042-7158
pISSN - 0022-3573
DOI - 10.1111/j.2042-7158.1958.tb10267.x
Subject(s) - histamine , liberation , mechanism (biology) , chemistry , pharmacology , medicine , biochemistry , philosophy , epistemology , in vitro
T heories have to be modified from time to time as fresh experimental data emerge. Recent years have brought new observations as to the localisation and the chemical binding of histamine in the tissues. Synthetic and biologically occurring histamine liberators constitute a new group of more or less specific substances and compounds, the histamine releasing properties of which were, until only a few years ago, completely unknown. The data available today necessitate reconsideration of the validity of existing theories on the mechanism of histamine liberation.